E[cyclo(RGDfK)]2
Chemical name:
H-Glu[cyclo(-Arg-Gly-Asp-D-Phe-Lys)]2
Cas-no.:
250612-47-6
Formula:
Molecular weight:
1318,44 g/mol
Quantity:
Price:
on request
Application
This cyclic RGD peptide possesses high affinity to integrin receptors localized on the surface of cancer cells. It can be easily conjugated to dyes, drug molecules, or chelators, like DOTA and NOTA.
References
- M.L. Janssen, W.J. Oyen, I. Dijkgraaf, L.F. Massuger, C. Frielink, D.S. Edwards, M. Rajopadhye, H. Boonstra, F.H. Corstens, O.C. Boerman. Cancer Res. 2002; 62(21): 6146-6151.
- Y. Wu, X. Zhang, Z. Xiong, Z. Cheng, D.R. Fisher, S. Liu, S.S. Gambhir, X. Chen. J. Nucl. Med. 2005; 46(10): 1707-1718.